The differential diagnosis of constitutional delay of puberty and hypogonadotropic hypogonadism in boys

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منابع مشابه

Congenital hypogonadotropic hypogonadism and constitutional delay of growth and puberty have distinct genetic architectures

OBJECTIVE Congenital hypogonadotropic hypogonadism (CHH) and constitutional delay of growth and puberty (CDGP) represent rare and common forms of GnRH deficiency, respectively. Both CDGP and CHH present with delayed puberty, and the distinction between these two entities during early adolescence is challenging. More than 30 genes have been implicated in CHH, while the genetic basis of CDGP is p...

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The Usefulness of GnRH and hCG Testing for the Differential Diagnosis of Delayed Puberty and Hypogonadotropic Hypogonadism in Prepubertal Boys

[Objective] Discrimination between hypogonadotropic hypogonadism (HH) and constitutional delayed puberty (DP) is difficult in prepubertal patients. We retrospectively analyzed the usefulness of the gonadotropin-releasing hormone (GnRH) test using time-resolved fluoroimmunoassay (TR-FIA) for the measurement of gonadotropins and the human chorionic gonadotropin (hCG) test to discriminate between ...

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Evaluation of near final height in boys with constitutional delay in growth and puberty

BACKGROUND This study was conducted to find out whether boys with constitutional delay in growth and puberty (CDGP) could attain their target height and predicted adult height (PAH) in adulthood or not. METHODS After measuring the height, weight, pubertal stage, parental height and bone age data of the patients at their first presentation were extracted from the files and their height and wei...

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Role of basal and provocative serum prolactin in differentiating idiopathic hypogonadotropic hypogonadism and constitutional delayed puberty--a diagnostic dilemma.

BACKGROUND The prevalence of Idiopathic Hypogonadotropic Hypogonadism (IHH) is approximately 1 in 10,000 men. Objectives of this study were to evaluate the role of basal and stimulated serum prolactin in differentiating Constitutional Delayed Puberty (CDP) from IHH. METHODS This cross-sectional study was carried out at the Department of Diabetes and Endocrinology, Military Hospital, Rawalpind...

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ژورنال

عنوان ژورنال: Problems of Endocrinology

سال: 2020

ISSN: 2308-1430,0375-9660

DOI: 10.14341/probl10339